What is documented by Advertisement for Subject Recruitment?

• A. The financial agreement between the investigator/institution and sponsor for the trial
• B. The trial's recruitment schedule
• C. The ethics committee approval letter
• D. The sponsor's promotional plan

Answer: (D)

In good clinical practice, recruitment advertising is governed by the sponsor’s promotional plan. This document specifies how recruitment messages will be created, where they’ll be used, the target population, and the wording to ensure messages are truthful, not coercive, and compliant with regulations. The advertisement for subject recruitment is essentially the implementation guide for how potential participants will be informed about the trial, which is why it is documented as the sponsor’s promotional plan. It’s not the financial agreement (that’s a contract between sponsor and site), nor the recruitment schedule (which is about timing rather than messaging), nor the ethics committee approval letter (that confirms ethical review but is a separate approval document).